The Walgreens located at 200 South Locust St. is projected to close on Nov. 15.
It is one of 150 closures nationwide announced by the pharmacy chain.
Shift lead Deborah Menche said that the Oxford store’s 15-20 employees have been offered positions at locations surrounding Oxford.
She said she believes the store was selected to be shuttered because of its location and the number of people who use the pharmacy for prescriptions.